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Lexapro blocks the re-absorption of serotonin by the first nerve cell. This medicine include nausea, vomiting, diarrhea, upset stomach, loss of appetite, dizziness, drowsiness, trouble sleeping. Lexapro blocks the re-absorption of serotonin by the first nerve cell. To use Lexapro for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient.