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You could have unpleasant withdrawal symptoms. Prednisone and Prednisolone are considered to be intermediate acting steroids, meaning that a dose lasts about a day or a day and a half. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Corticosteroids, including prednisone, are commonly used to suppress the immune system.
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