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Amlodipine is taken once daily and may be used alone or in combination with other drugs for high blood pressure and chest pain. Amlodipine relaxes the blood vessels, making it easier for the heart to pump and reducing its workload. Side effects of Amlodipine. While you are taking Amlodipine, as a slow reduction in the dose may be needed. Amlodipine is taken once daily and may be used alone or in combination with other drugs for high blood pressure and chest pain.

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